Solid Dispersion Pellets: An Efficient Pharmaceutical Approach to Enrich the Solubility and Dissolution Rate of Deferasirox
نویسندگان
چکیده
منابع مشابه
Solid Dispersion Approach Improving Dissolution Rate of Stiripentol: a Novel Antiepileptic Drug
Some drugs have low bioavailability due to their poor aqueous solubility and/or slowdissolution rate in biological fluids. Stiripentol (STP) is a novel anticonvulsant drug that isstructurally unrelated to the currently available antiepileptics. It has poor aqueous solubilityand its solubility has to be enhanced accordingly. Polyethyleneglycol 6000 (PEG-6000) iscommonly utilized as a hydrophilic...
متن کاملSolid Dispersion- an Approach to Enhance the Dissolution Rate of Aceclofenac by Using 3 Factorial Design
Aceclofenac is an analgesic and anti-inflammatory agent used in the management of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. The objective of the present work was to investigate the effect of different types of carriers such as polyvinyl pyrrolidone (PVP), polyethylene glycol (PEG) 6000 and sodium lauryl sulphate (SLS) as solubilizer on in vitro dissolution of aceclofenac....
متن کاملSolid Dispersion–an Approach to Enhance the Dissolution Rate of Amlodipine
Solid dispersion refers to the dispersion of one or more active ingredients in an inert carrier in a solid state, frequently prepared by the melting method, solvent method, or fusion solvent method. The oral bioavailability of poorly water soluble drug remains as the most challenging aspects of drug development. Solid dispersion approach is to reduce particle size, therefore increases the disso...
متن کاملthe aesthetic dimension of howard barkers art: a frankfurtian approach to scenes from an execution and no end of blame
رابطه ی میانِ هنر و شرایطِ اجتماعیِ زایش آن همواره در طولِ تاریخ دغدغه ی ذهنی و دل مشغولیِ اساسیِ منتقدان و نیز هنرمندان بوده است. از آنجا که هنر در قفس آهنیِ زندگیِ اجتماعی محبوس است، گسترش وابستگیِ آن با نهاد ها و اصولِ اجتماعی پیرامون، صرفِ نظر از هم سو بودن و یا غیرِ هم سو بودنِ آن نهاد ها، امری اجتناب ناپذیر به نظر می رسد. با این وجود پدیدار گشتنِ چنین مباحثِ حائز اهمییتی در میان منتقدین، با ظهورِ مکتب ما...
Solid Dispersion Approach Improving Dissolution Rate of Stiripentol: a Novel Antiepileptic Drug
Some drugs have low bioavailability due to their poor aqueous solubility and/or slowdissolution rate in biological fluids. Stiripentol (STP) is a novel anticonvulsant drug that isstructurally unrelated to the currently available antiepileptics. It has poor aqueous solubilityand its solubility has to be enhanced accordingly. Polyethyleneglycol 6000 (PEG-6000) iscommonly utilized as a hydrophilic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BioMed Research International
سال: 2020
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2020/8583540